Czech Republic's Top 10 Startups That Tech Professionals Should Watch Out For in 2025

The Czech Republic's startup ecosystem is seriously heating up, with over 300 innovation spaces and startup infrastructures driving growth in 2025.

Prague's buzzing tech scene has earned its spot as the "Silicon Valley of Central Europe," ranking 4th in Eastern Europe's startup scene. Czech startups are crushing it globally - venture capital investments hit US$92.39 million in 2024, with AI and cybersecurity startups leading the charge.

These aren't just random numbers; they show how Czech tech is leveling up. The country's got this amazing mix of talent, with STEM graduates making up 31% of the workforce, and over 470 startups in Prague alone creating next-level solutions.

Companies like Better Stack and Rossum are totally changing the game in their fields, while the government's backing everything up with smart policies and support.

The tech community's eyes are glued to what's happening here, and honestly, it's pretty incredible to watch. In the next sections, we'll break down the top 10 Czech startups that are absolutely nailing it in 2025, showing exactly why this scene is blowing up right now.

The Czech Republic's startup scene is seriously heating up! As a moderately competitive market with high political stability, the country's methodology for ranking top startups focuses on three key factors: funding prowess, tech innovation, and real-world impact.

The venture capital scene is growing fast, with projections showing total capital raised reaching $92.39 million by 2024.

Czech startups are crushing it in global innovation rankings - they're currently ranked 24th worldwide for innovation output, which is actually better than last year!

When looking at industry impact, it's amazing to see how these startups are changing the game.

Companies are pushing boundaries in AI, fintech, and especially in green tech solutions. The selection process digs deep into financial reports, market analysis, and feedback from people actually using these technologies.

What's really interesting is that about 60% of new Czech startups are incorporating AI into their core products - that's huge for staying competitive globally!

This analysis isn't just about throwing numbers around - it's about finding companies that are actually making a difference.

The research looks at how startups are solving real problems, whether it's making banking easier or helping the environment. Market experts are pretty excited about what's happening here, saying Czech startups are becoming major players in European tech innovation.

The focus on healthcare tech and fintech is particularly strong, with many companies in these sectors showing serious growth potential. It's honestly impressive to see how Czech startups are stepping up their game and competing on the global stage!

Better Stack's rise since 2021 has been nothing short of incredible. Based in Prague, this tech startup is crushing it with their infrastructure monitoring platform that's now used by over 200,000 developers and 4,000 customers worldwide.

What makes them stand out is how they've made complex monitoring tools super accessible - their platform combines everything from uptime checks to incident management in one place, and it's way cheaper than traditional options.

The company just secured €9.2 million in funding from KAYA, with some serious backing from tech leaders like Aaron Levie (Box CEO) and Kulpreet Singh (ex-UiPath).

Better Stack's success isn't just about the money - they've got some amazing clients like Time Magazine, Salesforce, ESET, and even UNICEF using their tools.

What's cool is how they've revolutionized infrastructure monitoring with features like Figma-style collaborative dashboards and AI-powered incident management.

The platform runs 10-100 times faster than alternatives, and the best part? They became profitable in early 2023 without even trying. Founded by Charles Johnson and Veronika Kolejak, Better Stack's team spans globally across countries like Slovakia, Romania, the US, and Rwanda, bringing fresh perspectives to solve engineering challenges.

Looking ahead to 2025, Better Stack is positioned to reshape how companies handle their tech infrastructure.

They're not just another monitoring tool - they're building what developers actually want to use. With plans for more AI features and expanding their reach, Better Stack shows how Czech tech startups can compete and win on the global stage.

Their focus on making powerful tools that are beautifully simple to use is exactly what today's fast-moving tech teams need.

Prague-based Blindspot Technologies has quickly become a game-changer in cybersecurity, focusing on advanced DDoS protection and machine learning solutions.

Their innovative approach caught major attention in November 2023 when they secured €1.4 million in funding from investors including Presto Ventures and the Gi21 fund.

- Rapid Deployment Capability: While most security solutions take months to implement, Blindspot gets the job done in days. - Traffic Monitoring and Protection: Their system offers both constant traffic monitoring and on-demand protection during attacks. - Custom-Fitted Solutions: Their team delivers custom-fitted solutions for each client, crucial for different company setups. - Innovative Approach: Their mission goes beyond just following industry trends - they're actively pushing boundaries in cybersecurity innovation. - Expansion Plans: Looking ahead, they're planning to expand into Southeast Asia, where cyber threats are becoming a major concern. - AI and Machine Learning: What's really cool is how they're using AI and machine learning to spot and stop attacks. With global cybercrime costs projected to hit $23.82 trillion by 2027, Blindspot's timing couldn't be better.

The company's success shows in their growing client base and the trust they've earned from businesses with seriously demanding security needs. Their focus on both web application and API security makes them a solid choice for businesses trying to stay ahead of cyber threats in 2025.

Founded in 2022 in Prague, Cruxo is transforming retail media with their smart platform that makes managing targeted ad campaigns actually simple.

Led by CEO Michal Trunkát and a team of industry veterans with 90 years of combined experience, they're crushing it in areas like pharmacy, beauty, and electronics.

Their platform is all about automating the tedious stuff - no more Excel sheets for campaign planning! Cruxo secured €800K in funding from Czech Founders VC, Presto Ventures, and ZAKA VC in 2023, showing investors are seriously backing their vision.

The retail media market is huge, like $100 billion huge, and Cruxo's got the tech to help retailers get a piece of that pie. They're taking inspiration from Amazon's success (who makes 8% revenue from retail media with a wild 90% profit margin) and making it possible for other retailers to achieve similar results.

Their data-driven approach helps both retailers and vendors boost sales through personalized offers that actually connect with shoppers.

What makes them stand out is how they've simplified the whole process - from planning to optimization - making it accessible for companies that want to level up their retail media game.

With real-time analytics and automated campaign management, they're basically giving retailers everything they need to compete in today's digital marketplace.

E2B.dev has emerged as a game-changing force in the AI development space since its founding in Prague. Under the leadership of CEO Michael Garcia, the startup has secured an impressive $11.5M seed round, surpassing initial expectations.

Their core product is an open-source infrastructure platform that enables developers to run AI-generated code in secure cloud sandboxes, starting up in just 150 milliseconds.

What makes E2B stand out is their focus on real-world applications - from data analysis to creating full AI-generated apps. They've really nailed the balance between security and functionality, with their code interpreter SDK supporting both JavaScript and Python, making it super flexible for different development needs.

The platform has caught the attention of major players in the tech world, showcasing its potential through impressive collaborations like their integration with Perplexity AI. E2B's approach to AI security isn't just about putting up walls - it's about creating a safe playground where AI can actually do its thing without compromising security.

The E2B GitHub repository has already gathered over 7,000 stars, showing strong community support and validation.

Their cloud runtime environment is built for both individual developers and enterprise teams, offering customizable CPU and RAM options to match specific project needs.

Looking ahead to 2025, E2B is positioned to become an essential tool in the AI development toolkit, especially as more companies seek secure ways to implement AI solutions.

Filuta AI, this super cool startup from Prague that's totally changing the automation game since 2022. Their platform makes intelligent automation accessible to everyone, not just tech experts, by breaking down complex problems into manageable pieces.

What makes them stand out is their use of something called Composite AI, which combines different types of AI to solve real-world problems way faster than traditional methods.

They've actually managed to break records with their $2.5 million pre-seed funding, which is the largest in Czech startup history.

Their technology is seriously impressive - it works 10 times faster than regular AI solutions, and you don't need to be a coding wizard to use it. What's really exciting is how they're expanding across different industries, from gaming and QA to logistics and manufacturing.

They've got some major backing from partners like CzechInvest and AIPlan4EU, plus they're getting support from the European Commission. For anyone looking to get into tech, this is exactly the kind of company you want to keep an eye on - they're making AI and automation something everyone can use, not just the tech experts.

The platform handles everything from testing to real-time monitoring, and it's already helping businesses work smarter, not harder.

GRAET is changing the game for athletes since its 2023 launch in Prague, creating a seriously cool platform that helps athletes show off their skills. Through innovative digital solutions and expert mentoring, GRAET connects athletes with scouts, fans, and sponsors while giving them total control over their personal brand.

What makes this platform stand out is how it brings together key features like financial management and social media promotion - similar to how MyTeam has revolutionized team management.

After securing $1.5 million in seed funding and another $5 million Series A round, GRAET is seriously crushing it. The platform is perfect for both pro athletes and up-and-comers, offering everything from highlight reels to performance stats.

What's really awesome is how they're streamlining athlete licensing and brand deals, making it super easy for athletes to monetize their talents.

The team behind GRAET gets that athletes need more than just exposure - they need real tools to build their careers. Their focus on Central European athletes is already helping put local talent on the global map, and by 2025, they're aiming to be the go-to platform for athlete self-promotion worldwide.

It's not just another social media platform - it's a complete career management system that's actually making a difference in how athletes build their futures.

KARDI AI, launched in 2022 in Olomouc, is transforming heart health monitoring with their groundbreaking partnership with Polar.

The startup's app connects to Polar's H10 chest sensor, letting users track their ECG data right from their phones - pretty neat for anyone worried about their heart health.

They've already helped detect over 220 cardiac events early, potentially saving lives.

Their AI-powered system gives instant feedback and lets doctors check your heart data remotely, which is honestly amazing for getting quick medical attention when needed.

The company's been crushing it with funding too.

They just secured €1.5 million in seed funding, and they're already getting ready for their Series A round.

With over 1,500 active users and more than 130 cardiologists and neurologists prescribing their tech, they're definitely making waves in healthcare. What's really impressive is that they're the first Czech startup to get MDR Class IIa certification, which basically means their tech is legit and safe for medical use.

Looking ahead, KARDI AI isn't just staying in the Czech Republic.

They're expanding into Poland, India, and the UAE, plus running pilot projects in Bulgaria, Romania, and Estonia. Their mission is all about making heart monitoring accessible and affordable for everyone, which honestly could change how we approach heart health forever.

They've even partnered with Škoda Auto Insurance and are talking to other insurance companies to make their technology available to more people.

Founded in 2023 in Brno, Lakmoos is revolutionizing market research with their neuro-symbolic AI that simulates how customers think and behave.

Led by CEO Kamila Zahradníčková, this tech startup builds data models that deliver instant insights, completely changing the game in customer intelligence. Their mission is ambitious - they're aiming to replace 20% of traditional surveys with real-time insights by 2030, which could save an incredible $30 billion in research costs and 35 billion hours of global fieldwork.

They've recently secured €300K in funding, showing that investors are backing their vision. What makes Lakmoos stand out is their ability to run everything from qualitative interviews to quantitative surveys, with pricing that's always below 20% of regular market research budgets.

Their tech covers multiple research types, including forecasting, media monitoring, and semantic search. Their innovative approach to market research has caught attention across industries like automotive, banking, and telecommunications.

With solutions starting at €3,000 for research projects and options for unlimited research at €3,200 monthly, they're making high-quality market insights accessible to businesses of all sizes.

The company currently has 25 employees and is positioned to scale rapidly as they continue to develop their AI-driven platform. For tech professionals watching the Czech startup scene, Lakmoos represents exactly the kind of innovation that's making Brno a serious tech hub.

Upheal, founded in 2021 in Prague, is revolutionizing mental health care with its AI-powered progress notes platform that's changing how therapists and psychiatrists work.

The startup has grown incredibly fast, raising an impressive €9.52 million in their Series A funding round, bringing their total funding to €13.65 million. What makes Upheal stand out is their focus on helping mental health professionals stay fully present during sessions while tackling the massive challenge of documentation.

Their platform is HIPAA compliant and works seamlessly with existing healthcare systems, making it super practical for real-world use.

Founded by Linda Brown and Martin Horváth, Upheal has proven its worth through impressive growth and adoption by mental health professionals.

The platform's AI technology doesn't just handle notes - it provides valuable insights and analytics that help therapists improve their practice. Real users are seeing major benefits, with many reporting they can finally focus on their clients instead of worrying about staying up late doing paperwork.

What's really cool is how Upheal is tackling burnout in the mental health field.

Their commitment to provider well-being includes offering a free plan to ensure all mental health professionals can access tools that make their work more manageable.

The platform doesn't store recordings and gives users complete control over their data, which is crucial in mental healthcare. With regular security audits and strict privacy measures, Upheal is showing how tech can make therapy better while keeping everything secure and confidential.

Founded in 2023, Wopee.io is changing the game in web application testing with their autonomous testing bot that crawls through applications in just minutes.

The startup, backed by three major investors including StartupYard - Central Europe's leading seed accelerator - has proven that testing doesn't need to be complicated.

Their self-driving bot can set up tests in one minute and deliver results in seconds, without requiring any coding knowledge. What's especially cool is that it achieves 50-70% faster execution times and 5x higher coverage compared to traditional testing methods.

The team behind Wopee.io includes some serious talent, with experienced developers and test automation engineers like John Rodriguez and Marcel Veselka, who bring decades of combined experience in software testing.

Their innovative approach tackles common testing headaches - like the fact that 90% of testers face delays due to complex tools and manual testing. The bot handles everything from visual regression testing to exploratory testing, making it perfect for engineering teams who want to speed up their workflow without sacrificing quality.

Real users are already seeing amazing results.

Martin Šimon, Test Automation Lead at Livesport, points out how Wopee saves precious time in maintaining visual integrity, while Juraj Žabka from Multitude praises its effectiveness in testing marketing and customer account pages.

The platform's success hasn't gone unnoticed - they've secured backing from Tesena s.r.o., Nation 1, and StartupYard, positioning them perfectly for rapid growth in the autonomous software testing market.

By making testing more accessible and efficient, Wopee.io is seriously disrupting the traditional QA landscape and setting new standards for web development practices.

The Czech startup scene is absolutely crushing it right now, and it's only getting better as we head into 2025. The country ranks 3rd in Eastern Europe and 32nd globally for its startup ecosystem, which is seriously impressive for a nation of just 10.5 million people.

The numbers are wild - Prague alone has over 700 startups, and the whole ecosystem is backed by some really smart government moves, like their startup visa program that's bringing in fresh talent from everywhere.

What's really cool is that the Czech Republic's ICT revenues are expected to hit $24.3 billion by 2026, with major growth in software development and cybersecurity.

These aren't just random startups either - we're talking about companies that are changing the game in everything from e-commerce to healthtech. Venture capital investment is projected to reach $92.39 million in 2024, and that's just the beginning.

The startup scene has this perfect mix of low living costs, great tech talent, and a central location in Europe that's making international investors take notice.

For anyone in tech looking to make their mark, the Czech Republic is basically becoming the new hot spot for innovation in Europe. The energy here is incredible, and honestly, if you're not paying attention to what's happening in this space, you're missing out on something big.