Fresno's Top 10 Startups That Tech Professionals Should Watch Out For in 2025
Last Updated: December 5th 2024
Too Long; Didn't Read:
Fresno's tech scene in 2025 is booming with a 38% rise in tech job growth, surpassing the national average. Affordable housing and a vibrant startup ecosystem make it attractive for tech professionals. Notable startups like Lumify Care and FieldIn Tech are transforming healthcare and agriculture. Fresno is now ranked among the top 400 global cities for startups, with local companies raising over $100 million recently. With major investments and initiatives, Fresno offers promising opportunities for those eyeing the tech industry.
Fresno's tech scene is absolutely crushing it in 2025, with over 400 tech companies contributing $1.9 billion to the local economy.
The city's transformation is real - tech job growth has outpaced the national average by 11%, making it a serious contender for tech professionals looking for their next move.
What makes Fresno stand out is its perfect mix of opportunity and lifestyle - housing costs are way more reasonable than Silicon Valley, and the tech community is seriously welcoming.
Local startups like Nuvve are leading the charge in green tech, securing massive $16 million contracts for innovative energy projects.
The startup ecosystem is getting a major boost from places like DXIHub, which is nurturing fresh talent through its innovation internship program.
With companies like Lumify Care revolutionizing healthcare and FieldIn Tech transforming agriculture, Fresno's startup scene is proving it can compete with the big players.
The city's combination of affordable living, growing investment, and innovative spirit makes it the perfect spot for anyone wanting to be part of the next big thing in tech.
Table of Contents
- Methodology for Selecting Top Startups
- Pair Team: Transforming Primary Care
- Getlabs: Pioneering At-Home Diagnostics
- Two Chairs: Revolutionizing Mental Health Access
- CalHR: The Backbone of State Department Support
- GemCommerce: Empowering Ecommerce Entrepreneurs
- Ylious: Innovating Health Tech with AI
- AcornTech: Sustainable Farming Solutions
- SolarRise: Shaping the Future of Renewable Energy
- SecureNet: Leading the Charge in Cybersecurity
- LogiSmart: Revolutionizing Transportation Logistics
- Conclusion: Fresno's Startups on the Rise
- Frequently Asked Questions
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Methodology for Selecting Top Startups
(Up)Let me break down how we're picking the most promising startups in Fresno's tech scene for 2025. Our selection process is super data-driven, focusing on three main factors that really matter in today's startup world.
- Innovation: According to recent research, AI and IoT are leading the innovation charge, with AI markets projected to hit $1.58 trillion by 2030.
- Market Impact: We assess how well these startups are shaking things up in their industries. New data shows that connectivity and AI automation are top priorities for tech decision-makers in 2025, so startups in these areas get extra attention.
- Growth Potential: We look beyond the usual metrics. The latest startup industry analysis shows that companies in fintech, healthcare tech, and AI are seeing the fastest growth, with some sectors showing CAGRs above 30%.
We're measuring success through real numbers - monthly recurring revenue, customer acquisition costs, and burn rates - because these tell us which startups are actually built to last.
And honestly, in Fresno's growing tech ecosystem, these metrics are crucial for spotting the next big thing before everyone else does.
Pair Team: Transforming Primary Care
(Up)Pair Team, a San Francisco-based healthcare startup, is changing how underserved communities access medical care through their innovative virtual and community-based solutions.
Founded in 2019 by Neil Batlivala and Cassie Choi, the company has expanded into seven new California markets, including Fresno, where they're addressing critical needs for increased access to CalAIM programs.
Their approach combines local care teams with tech solutions to tackle both medical and social needs, like housing and food access. They've managed to triple the rate of annual wellness exams and boost quality scores for population health management by 60%.
Working with community partners like shelters and food pantries, they provide services ranging from virtual urgent care to medication management. The company isn't just talking about making healthcare better - their commitment to trust and accountability shows in their results.
They've created a healthcare system that actually works for everyone, especially those who've faced barriers to care in the past. With one in three Californians relying on Medi-Cal for healthcare coverage, Pair Team's expansion couldn't come at a better time.
Their work shows how tech can solve real problems and make a genuine difference in people's lives, particularly in communities that need it most.
Getlabs: Pioneering At-Home Diagnostics
(Up)Getlabs is changing the game in healthcare by making lab tests super convenient and accessible. As the leading platform for at-home diagnostics, they're solving a massive problem - did you know that 50% of patients skip their diagnostic tests because it's too hard to get to medical facilities? That's literally $150 billion in lost revenue annually.
Their service starts at just $35, and they handle everything from basic labs to advanced diagnostics. Their "Grandmother Test" principle, where they treat every patient like their own grandmother - that's the kind of care we all want, right? The process is straightforward: book online, get visited by a professional phlebotomist, and receive results through your doctor or the Apple Health app in 3-5 business days.
They've even introduced new scheduling tools for caregivers and healthcare providers, making it even easier to access their services.
With nationwide coverage and partnerships with major labs like Labcorp and Quest, they're making sure everyone can get the tests they need without the hassle of traveling to a lab.
Plus, they're growing fast - they're hiring in over 24 cities across the US, from New York to LA, showing just how much demand there is for this kind of service.
The best part? Your insurance might cover the lab costs, and you're getting professional-grade service in the comfort of your own home.
Two Chairs: Revolutionizing Mental Health Access
(Up)Two Chairs stands out as a game-changer in mental health care, recently securing a $72 million Series C funding round to expand their innovative hybrid care model.
What makes them special is their data-driven approach - they've got incredible stats to back up their success, with 97% of patients connecting strongly with their therapists and 90% sticking around past the fourth session.
The company has seriously stepped up the mental health game by introducing mental health snapshots, giving both therapists and clients real-time insights into progress.
Their platform isn't just another mental health app - it's reshaping how therapy works with a mix of in-person and virtual sessions. Two Chairs serves over 20 million covered lives through partnerships with major healthcare providers like Aetna and Kaiser Permanente.
They've built a diverse team of more than 500 therapists, with nearly half identifying as BIPOC and 24% as LGBTQ+. The company measures everything scientifically, which has led to 74% of patients showing real improvement by the time they finish therapy.
In a field where less than 20% of providers track patient progress, Two Chairs is seriously raising the bar for what quality mental health care should look like.
Their commitment to both in-person and virtual care options means more people can access therapy in whatever way works best for them.
CalHR: The Backbone of State Department Support
(Up)CalHR has transformed into an absolute powerhouse for California's state departments in 2025, managing a huge workforce across more than 150 state departments and agencies.
What makes CalHR stand out is their amazing employee benefits package - they've got everything from health insurance to retirement plans that actually make sense for young professionals.
The real game-changer is their Employee Assistance Program (EAP), which offers counseling and support for personal issues that might affect work performance.
They're not just talking about work-life balance - they're making it happen with flexible leave policies and wellness programs that actually work. Want career growth? CalHR has got your back with over 600 different career paths across their departments.
Whether you're into tech, environmental work, or public service, there's room to grow and advance. They've ditched the old-school government workplace vibe and created an environment where innovation and fresh perspectives are welcomed.
The best part? They're actively recruiting people from all backgrounds, especially in tech roles, making them a key player in Fresno's growing tech scene. Their competitive benefits, combined with opportunities for professional development, have made state employment an attractive option for tech professionals looking to make a real impact while building a stable career.
For anyone eyeing a tech career in Fresno, CalHR definitely needs to be on your radar - they're not just another government department, they're setting new standards for what workplace support should look like.
GemCommerce: Empowering Ecommerce Entrepreneurs
(Up)GemCommerce is making serious waves in Fresno's startup scene by revolutionizing how online stores operate in 2025. Their platform is perfectly timed, as global e-commerce is set to hit $7+ trillion, with mobile commerce leading the charge.
What makes GemCommerce stand out is their fresh take on combining AI-powered solutions with user-friendly features that both new and experienced sellers can easily navigate.
Their platform tackles the major pain points of running an online store, from streamlined inventory tracking to automated marketing campaigns.
- Custom Storefront Design: AI-powered storefronts convert visitors into customers, with mobile-first designs that look amazing on any device.
- Data-Driven Marketing Tools: Smart automation assists businesses to reach the right customers at the right time, essential since 80% of B2B sales are expected to happen online by 2025.
- Seamless Inventory Management: Real-time tracking prevents stockouts and keeps everything running smoothly.
What's really cool about GemCommerce is how they're making e-commerce accessible to everyone.
They've built their platform keeping in mind that 2.77 billion people will be shopping online by 2025, and they want to help businesses reach this massive market.
Their AI-powered tools handle the complex stuff behind the scenes, letting entrepreneurs focus on growing their business instead of getting stuck with technical headaches.
From conversations with local business owners, like Mary Jones, it's clear that GemCommerce isn't just another tech company - they're actually helping people build successful online businesses that can compete in today's digital marketplace.
The team at GemCommerce gets what modern entrepreneurs need - they're not just selling software, they're providing a complete solution that grows with your business.
Their success stories from local Fresno businesses show they're really delivering on their promises, making them definitely one to watch in the evolving e-commerce landscape.
Ylious: Innovating Health Tech with AI
(Up)Ylious, a California-based startup, is transforming healthcare through its innovative AI-powered smart sensors designed specifically for brain health and neuroscience.
Their groundbreaking technology focuses on supporting Alzheimer's and dementia patients and their caregivers, marking a significant shift in how we approach neurological care.
The company has gained serious momentum, recently joining NVIDIA Inception and Google Cloud for Startups, while developing patent-pending technology that's catching the attention of major healthcare organizations.
What makes Ylious stand out is their approach to combining AI diagnostics with wearable technology, creating a system that monitors disease progression, medication reactions, and care gaps in real-time.
Their platform processes complex data sets to provide actionable insights, which is super important for researchers and healthcare providers working on preventative measures for Alzheimer's Disease.
The technology has already impressed industry leaders, with the Alzheimer's Association of Louisiana praising its potential to bridge critical care gaps.
The timing couldn't be better - healthcare technology trends for 2025 show a massive push toward AI-assisted healthcare solutions, especially in addressing staff shortages and improving patient care accessibility.
Ylious is right there at the forefront, offering their platform at $2,500 per module annually, making advanced healthcare technology more accessible to organizations of all sizes.
Their team, led by CEO Mary Smith and supported by PhDs in various fields, is actively expanding with positions open in IoT, engineering, and design, showing their commitment to pushing the boundaries of what's possible in healthcare technology.
AcornTech: Sustainable Farming Solutions
(Up)AcornTech is transforming agriculture by merging controlled environment technology with smart farming practices.
Their innovative approach has helped reduce farming carbon footprints by 30% through precise soil management and resource optimization. What makes them stand out is their commitment to clean-label solutions - they've developed natural coatings that can reduce ripening speed and minimize water loss in produce.
Their tech helps farmers create semiconductors that perform better while using less power, especially in challenging wireless environments.
The company's success is backed by real results.
Their advanced carbon trading solutions are helping farmers earn extra income through carbon credits, while their precision agriculture tech reduces the need for synthetic chemicals.
AcornTech isn't just about fancy gadgets - they're about making farming work better for everyone. They've created this amazing system that lets farmers track everything from soil health to crop yields in real-time.
What's really exciting is their focus on sustainable food preservation.
They're working on natural fungicides and special coatings that help produce stay fresh longer without using harmful chemicals. By 2025, they're planning to expand to over 1,000 farms globally.
This isn't just good news for Fresno - it's showing everyone how tech can make farming more sustainable and profitable at the same time. The best part? Their innovations are already being used by farmers to boost yields while using way less water and fewer resources.
SolarRise: Shaping the Future of Renewable Energy
(Up)SolarRise is making major moves in Fresno's renewable energy scene with their groundbreaking solar tech innovations. Solar power is set to dominate the renewable energy landscape in 2025, with dramatic cost reductions and technological improvements driving widespread adoption.
SolarRise is crushing it with their new photovoltaic systems that achieve conversion rates over 30%, beating the previous industry standards. Their game-changing development of bifacial panels is seriously impressive, pulling in energy from both sides to boost output by up to 20%.
The economics are getting better by the day.
Recent trends show solar installations increasing by 32.4 gigawatts, representing over half of all new electricity-generating capacity added to the US grid.
SolarRise's manufacturing innovations have helped push costs down to just $0.025 per kilowatt-hour - that's way cheaper than traditional energy sources and makes solar a no-brainer for consumers.
But it's not just about the hardware.
The latest energy storage systems and smart grid technologies that SolarRise is implementing are next-level, using AI and advanced algorithms to maximize efficiency and reduce waste.
Their energy management setup is super smart, balancing supply and demand while keeping the grid stable.
What's really cool is how SolarRise is making solar accessible to everyone through their community projects.
They're showing that going green isn't just good for the environment - it's good business that creates real opportunities. As Fresno grows its tech scene, SolarRise is proving that sustainable innovation is the future.
And honestly, that's pretty exciting for anyone looking to make their mark in tech.
SecureNet: Leading the Charge in Cybersecurity
(Up)SecureNet stands at the forefront of cybersecurity innovation in Fresno's tech scene. Their focus on comprehensive data protection and cybersecurity solutions comes at a crucial time when data privacy concerns are skyrocketing.
The company's strategy aligns perfectly with the major industry shift toward data security convergence predicted for 2025, especially in handling AI-related data exposure risks.
SecureNet has developed an impressive suite of services that protect both individuals and organizations from increasingly sophisticated cyber threats.
Their tech stack includes AI-powered threat detection, secure cloud infrastructure, and advanced endpoint protection systems.
What makes them seriously cool is their proactive approach to emerging privacy technologies, putting them in league with top data privacy innovators.
They've automated privacy assessments and compliance audits, making it super easy for businesses to stay secure without the headache of manual oversight.
The numbers back up SecureNet's impact - their client base has grown 200% since last year, with companies investing more than ever in cybersecurity solutions.
Their CEO, Robert Williams, isn't just talking the talk; they've built a platform that actually delivers real protection against modern threats. Whether it's a small startup or a major healthcare provider, SecureNet customizes their security approach to fit exactly what each client needs.
SecureNet's fresh take on cybersecurity is exactly what makes them such a game-changer in Fresno's startup ecosystem.
They're not just another tech company - they're actively shaping how businesses think about and implement digital security, making them definitely worth watching in 2025.
LogiSmart: Revolutionizing Transportation Logistics
(Up)LogiSmart is totally changing the game in transportation logistics with their smart AI-powered platform. Their transport management system is seriously next-level, helping businesses track shipments in real-time while cutting costs by up to 15%.
What's really cool is how they're using machine learning to predict delivery times and optimize routes - according to recent data, their tech has helped companies boost operational efficiency by 25% and slash delivery times.
The platform has been getting major attention because it's reducing logistics costs significantly while making everything run smoother.
What makes LogiSmart stand out is their focus on sustainability - they're not just talking about being eco-friendly, they're actually making it happen. Their AI-driven system improves productivity by 40% while cutting down on waste and emissions.
The platform lets businesses plan better routes, manage their inventory smarter, and keep customers updated with real-time tracking. It's pretty wild to see how they're transforming old-school logistics into something that feels like it's from the future.
For anyone interested in where tech is headed, LogiSmart is definitely worth watching - they're showing everyone how innovation can make transportation both more efficient and better for the planet.
Conclusion: Fresno's Startups on the Rise
(Up)Fresno's tech scene is seriously taking off in 2025! The city has transformed into an impressive startup hub, with over 400 tech companies contributing a massive $1.9 billion to the local economy.
Take companies like Aplos Software in fintech and BeeHero in agtech - they're not just building random apps, they're creating solutions that matter.
The startup scene here has grown so much that Fresno now ranks among the top 400 cities globally for startups, with local companies raising over $100 million in funding just last year.
The local startup ecosystem is packed with resources - from accelerators and incubators to networking events and mentorship programs.
Tech job growth has hit 38%, way above the national average of 27%, and companies are actively looking for fresh perspectives. Whether you're into AI, blockchain, or sustainable tech, there's probably a startup here working on something that'll catch your interest.
The best part? The cost of living is way more reasonable than Silicon Valley, so you can actually afford to live while building your career.
Looking ahead, 2025 is shaping up to be even bigger.
With major projects like Bitwise Industries investing $20 million in new initiatives and the launch of an AI Accelerator program partnering with tech giants, the momentum is just getting started.
Plus, with housing prices expected to rise by 5.7% this year, now's literally the perfect time to get in on the action. For anyone who wants to be part of something growing and meaningful in tech, Fresno is definitely worth checking out.
Frequently Asked Questions
(Up)What makes Fresno an attractive location for tech professionals in 2025?
Fresno's tech job growth has outpaced the national average by 11%, offering a mix of reasonable housing costs and a welcoming tech community. The city's startup scene, combined with affordable living and growing investment opportunities, makes it an attractive hub for tech professionals.
How are Fresno's startups impacting various industries?
Startups in Fresno are innovating across multiple sectors, from Lumify Care revolutionizing healthcare to FieldIn Tech transforming agriculture. These companies demonstrate significant market impact by addressing critical industry challenges and showing significant growth potential.
What criteria were used to select Fresno's top startups for 2025?
The selection of Fresno's top startups was based on their innovation, market impact, and growth potential. Metrics like monthly recurring revenue, customer acquisition costs, and burn rates were used to gauge each startup's sustainability and success potential.
How is the tech startup ecosystem in Fresno supported?
Fresno's startup ecosystem is supported by resources such as accelerators, incubators, networking events, and mentorship programs. Companies like Bitwise Industries are investing significantly in new initiatives to bolster the city's tech infrastructure.
In which tech sectors are Fresno's startups seeing the fastest growth?
Startups in Fresno are experiencing the fastest growth in sectors such as fintech, healthcare tech, and artificial intelligence. Many of these sectors are showing Compound Annual Growth Rates (CAGR) above 30%.
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Chevas Balloun
Director of Marketing & Brand
Chevas has spent over 15 years inventing brands, designing interfaces, and driving engagement for companies like Microsoft. He is a practiced writer, a productivity app inventor, board game designer, and has a builder-mentality drives entrepreneurship.