Top 10 Tech Companies to Work for in Winston Salem in 2025

Winston Salem is seriously making waves as a tech powerhouse in 2025, and it's incredible to see how far we've come. The recent designation as one of 31 national tech hubs has totally changed the game.

The Wake Forest Innovation Quarter is absolutely crushing it, spanning over 240 acres and housing more than 115 companies with 4,500+ workers. What's really exciting is seeing companies like Inmar Intelligence and Wake Forest Innovations leading the charge in areas like digital analytics and biomedical engineering.

The city's getting massive attention from investors, especially with major developments in life sciences and tech-oriented startups.

What makes this even better is how the Innovation Quarter keeps expanding with new office spaces, labs, and even cool spots like coffee houses and loft apartments.

For someone like me looking to break into tech, it's awesome to see how the city's creating opportunities through startup accelerators and tech education programs.

The best part? Companies here aren't just about the tech - they're offering real competitive benefits and amazing growth opportunities that make staying in Winston Salem a no-brainer for young professionals.

The tech landscape in 2025 is transforming how we pick top employers in Winston Salem. According to recent industry research, 64% of organizations are increasing their IT budgets, making it crucial to understand which companies are really investing in their future.

When looking at potential employers, I'm checking out three main things: their commitment to innovation, their financial stability, and their growth potential.

Forrester's latest predictions show that companies are shifting from just experimenting with tech to actually making it work for their bottom line - that's exactly what we want to see in a potential employer.

The selection process also considers how companies handle emerging technologies like AI and cybersecurity, since connectivity and AI are leading priorities for tech decision-makers in 2025.

The most promising companies aren't just talking about innovation - they're backing it up with serious investment in both technology and talent. We're looking at factors like their training programs, remote work policies, and whether they're actually using the cool tech they claim to be developing.

The best employers are showing they can adapt to rapid changes while keeping their teams engaged and growing. The companies that make our list aren't just good places to work right now; they're the ones setting themselves up to be industry leaders for years to come.

That means looking beyond just the paycheck to see which companies are investing in their people, their tech stack, and their future.

mPATH Health is making waves in Winston-Salem's tech scene as a groundbreaking digital health platform that's changing how we handle preventive care.

Founded in 2021, they've just secured a massive $3 million funding round, including $2 million from the National Cancer Institute and $1 million from Oncology Ventures.

mPATH is how they're doubling cancer screening rates across different communities, making healthcare more accessible for everyone.

Their cloud-based program uses automation and behavioral science to identify people who need screening tests and connects them directly to care providers. The company partners with major healthcare organizations like Atrium Health Wake Forest Baptist and UNC Health, showing they're seriously committed to improving healthcare delivery.

What makes mPATH stand out is their focus on health equity - they're not just building tech, they're making sure it works for people from all backgrounds and income levels.

With over $6M in total funding from the National Institutes of Health, they're proving that tech startups can make a real difference in healthcare while building a sustainable business.

For tech professionals looking to work in healthcare innovation, mPATH offers roles that combine cutting-edge technology with meaningful impact on people's lives.

Salem Cyber stands out as a rising star in Winston-Salem's tech scene, bringing next-level AI security solutions to protect against the wild cybersecurity threats of 2025.

Their AI-powered platform learns business context to automatically investigate cyber alerts, making security management actually manageable.

Just this year, they secured a fresh $550,000 investment, proving investors are seriously backing their vision. According to cybersecurity experts, AI-driven automation will dominate security budgets in 2025, especially for cloud security and zero-trust architectures - exactly where Salem Cyber excels.

With cybersecurity spending expected to jump 15% this year and make up 10-20% of IT budgets, Salem Cyber is perfectly positioned to grow even more.

• Team Expansion: Their team has expanded 40% since 2023, with plans to add 200 new jobs by the end of 2025.
• Job Opportunities: They're always looking for fresh talent in roles like AI Security Analysts, Cyber Threat Engineers, and Customer Success Managers.
• Hands-on Experience: For anyone interested in cybersecurity, Salem Cyber offers real hands-on experience with cutting-edge AI tech.
• Innovation in Tech Scene: They've totally changed the game for Winston-Salem's tech scene, bringing innovative security solutions and job opportunities.

Bringing innovative security solutions and awesome job opportunities to the area.

Brinter Inc stands at the cutting edge of biotech innovation in 2025, making waves with their advanced regenerative medicine and 3D biocomposite implants.

Their groundbreaking BioMods technology focuses on creating 100% resorbable implants that revolutionize tissue regeneration, particularly in orthopedics and sports medicine.

Brinter isn't just staying earthbound - they're literally taking bioprinting to space! Their collaboration with the International Space Station is testing how microgravity affects 3D-printed cell constructs, which could be game-changing for creating complex tissue structures.

In space, cells can grow without spatial restrictions, meaning we might soon print organs and tissues that are impossible to create on Earth. The company's innovation streak continues with their latest medical print head technology, which minimizes material waste and ensures precise printing of living cells.

For tech enthusiasts and bioengineers looking to make a real difference, Brinter is actively hiring top talent in Winston-Salem, NC. Their work isn't just about cool technology - it's about creating actual solutions for people who need tissue repairs and implants.

With the global bioprinting market expanding rapidly, Brinter's commitment to both earthbound and space-based research puts them at the forefront of medical innovation, making them an incredible place to kick-start a career in biotech.

In 2025, ONE DONATION is transforming philanthropy through its innovative digital platform that makes charitable giving super accessible and efficient. Following current nonprofit trends, the platform integrates cutting-edge technology with community-focused giving, creating an experience that totally gets how modern donors want to contribute.

The platform has revolutionized workplace philanthropy by letting employees donate straight from their paycheck and offering really cool features like private stock donations - which is pretty amazing since more companies are staying private longer.

What makes ONE DONATION stand out is its smart use of AI and data analytics to personalize the giving experience. According to recent studies, organizations using integrated fundraising technology are crushing their goals, with 76% meeting or exceeding their targets.

The platform's mobile-first approach and user-friendly interface make it super easy for donors to track their impact in real-time, which is exactly what younger generations are looking for.

With features like automated donation matching, blockchain-secured transactions, and personalized cause recommendations, ONE DONATION is seriously changing how we think about charitable giving.

For anyone looking to work in tech while making a real difference, ONE DONATION offers some incredible opportunities in roles like AI development, UX design, and blockchain engineering.

The company's recent $10 million funding round shows that investors are totally backing this vision of making philanthropy more accessible and impactful through technology.

SWIPEBY has totally transformed from its 2017 roots into a game-changing AI-driven business automation platform that's crushing it in Winston-Salem's tech scene.

What started as a simple idea has evolved into a comprehensive solution that's changing how local businesses handle everything from customer service to social media.

Their secret sauce? A mix of AI-powered tools that handle tasks like review management and personalized marketing, letting businesses focus on what they do best.

SWIPEBY's innovative approach to digitization has been especially crucial for independent food retailers trying to keep up with bigger chains.

The platform's ability to create virtual drive-thrus and manage curbside pickup has been a total game-changer, especially since the pandemic changed how we all shop and eat.

What's super interesting is their subscription model for retailers, which runs less than $100 monthly per location - making it actually affordable for small businesses to compete with the big players.

They've gotten pretty creative with their tech stack too, using geofencing to streamline pickup operations and AI to handle everything from phone calls to social media posts.

The company has raised $1.12M so far and keeps expanding their reach, working with all kinds of businesses from restaurants to convenience stores. For anyone looking to jump into tech in Winston-Salem, SWIPEBY offers a chance to work with cutting-edge AI and automation tools while helping local businesses thrive in the digital age.

Senteon is making waves in cybersecurity by automating compliance and endpoint security across workstations, servers, and browsers.

Their innovative approach caught attention at IT Nation Connect 2024, where they were named one of the top three finalists in a competitive tech showcase.

What sets them apart is their fresh take on tackling cyber threats - they've built a platform that actually makes security management less of a headache. For tech professionals looking to join their team, Senteon offers roles in developing cutting-edge solutions that help organizations meet strict compliance standards like NIST, HIPAA, and PCI DSS. The company's multi-tenant dashboard system lets teams handle security across different client environments without getting overwhelmed.

Working at Senteon means getting hands-on experience with real-time monitoring, automated compliance reporting, and AI-driven threat detection - skills that are super valuable in today's job market.

They're growing fast and constantly pushing boundaries in automated security, which means plenty of opportunities to grow your career while working on tech that matters.

Plus, with cybersecurity automation becoming more critical every day, joining Senteon now could set you up for an awesome career trajectory. The company culture focuses on innovation and staying ahead of cyber threats, so if you're into solving complex problems and want to work with the latest security tech, this could be your perfect match.

OrbitalRx is transforming healthcare technology in Winston Salem with their all-in-one platform for drug shortage management.

Created by pharmacists who understand real-world challenges, their system helps healthcare providers tackle drug shortages head-on. The platform has shown impressive results, with users reporting a 50% reduction in workload and saving 288 hours analyzing new shortages.

Through a game-changing collaboration with IBM Watson Health, OrbitalRx now combines artificial intelligence with drug inventory management, making their solution even more powerful.

Their innovative approach caught attention nationwide, leading to their membership in the End Drug Shortages Alliance, where they work with hospitals across the country to increase supply chain transparency.

The company's growth creates exciting opportunities for tech professionals, particularly in data analysis, software development, and health informatics.

Their team builds cutting-edge solutions that combine predictive analytics with real-time inventory tracking, making drug shortage management more efficient than ever.

For entry-level tech professionals, OrbitalRx offers a chance to work with advanced AI applications while making a real difference in healthcare. The platform's success is backed by real results - pharmacy buyers report saving 8-10 hours weekly, while health systems benefit from streamlined operations and improved patient care outcomes.

OrbitalRx offers roles focused on:

• Software Engineering: Building and maintaining the core platform
• Data Science: Working with AI and predictive analytics
• Product Development: Creating solutions for healthcare challenges

With Winston Salem's growing tech scene and OrbitalRx's innovative approach to healthcare technology, the company stands out as a prime destination for tech professionals looking to make an impact in healthcare while working with cutting-edge technology.

In 2025, Fluree has become a total game-changer in Web3 data management and AI innovation. Since its founding in 2016, this Winston-Salem tech company has revolutionized how businesses handle their data through blockchain and semantic graph technology.

The real breakthrough came when they secured a $10 million Series A funding round led by SineWave Ventures, pushing their total funding to $16.5 million.

This investment has supercharged their development of data-centric infrastructure for verifiable credentials and decentralized data management. What makes Fluree seriously cool is how they've open-sourced their entire platform, letting developers worldwide contribute to building a more secure and connected digital future.

Their tech stack combines AI capabilities with knowledge graphs, making data not just more accessible but also more trustworthy. According to Gartner, graph technologies like Fluree's are expected to be used in 80% of data and analytics innovations by 2025, up from just 10% in 2021.

The company has earned major street cred by landing contracts with the Department of Defense and Air Force, proving they're not just another startup with big dreams but a serious player in the tech world.

For anyone looking to break into tech in Winston-Salem, Fluree represents exactly where the industry is heading - a perfect blend of innovative technology and practical business solutions.

MotorCo Apps is making real waves in 2025 as the first mobile app developer combining location-based applications with Virtual Reality.

The tech is pretty mind-blowing - they're creating these super interactive experiences that mix real-world data with digital elements. According to recent industry projections, the global AR/VR market is set to hit $165.2 billion by 2032, which is huge considering it was only at $24.9 billion in 2023.

What's really cool is how they're using this tech - from helping medical students practice procedures to letting tourists explore destinations before they even get there.

The company's growth is perfect timing too, since Tech Trends 2025 shows that VR and AR are becoming major players in robotics and automation.

The best part? They're creating tons of jobs right here in Winston Salem.

• Gaming opportunities: If you're into gaming, MotorCo Apps is definitely worth checking out.
• Healthcare tech: They help medical students practice procedures with advanced technology.
• Creating cool experiences: For those who love creating digital experiences, this is the right place.

They're not just following trends - they're creating them, making Winston Salem a serious contender in the tech world.

Whether you're a developer, designer, or data analyst, there's room to grow and create something amazing. The future of tech is happening right now, and it's pretty exciting to see it unfold in our own backyard.

Riot Golf is transforming the golf fashion game in 2025, making waves with their fresh approach to design-forward golf accessories.

Their latest collections blend performance with style, featuring moisture-wicking fabrics and UV protection that keep players comfortable during those long days on the course.

What's really cool is how technology meets tradition in their designs - they're not just making standard golf gear, they're creating pieces that actually enhance your game.

The brand started with a focus on footwear accessories, but has quickly expanded their lineup to include a full range of tech-integrated items that are seriously changing how we think about golf fashion.

Looking at 2025's golf accessory trends, Riot Golf stands out for their smart integration of performance features with streetwear-inspired designs.

Their commitment to innovation shows in their growing collection of accessories that help players express their personality while improving their performance.

The best part? They're making golf style accessible and exciting for a new generation of players who want their gear to work as hard as they do.

Winston Salem is absolutely crushing it in the tech scene right now! Recent economic reports show employment growing 1% above state and national averages, with 26 projects creating 1,814 new jobs and bringing in $667 million in investments.

The city's becoming super attractive for tech professionals, especially with Winston Salem ranking #2 for Women in Tech and offering amazing internet speeds of 463.66 Mbps - perfect for remote work! What's really cool is that we're seeing tons of AI and cloud computing roles opening up, with local businesses investing heavily in AI and ML, projecting a 25% job growth in these areas over the next three years.

The city's got this perfect mix of startup energy and established tech companies.

Places like Flywheel and Winston Starts are giving new companies the boost they need, while bigger players are expanding their operations. Tech salaries are competitive, and the best part? The cost of living is way lower than in tech hubs like San Francisco or New York.

Plus, with 56 potential projects in the pipeline that could create up to 11,000 new jobs and bring in $7 billion in investment, the future's looking seriously bright for anyone wanting to build a tech career here.

For anyone looking to break into tech, Winston Salem offers seriously good opportunities to grow.

Between the collaborative tech community, affordable living costs, and growing job market, it's becoming a real powerhouse for innovation. Whether you're into AI, cybersecurity, or web development, there's space for everyone to make their mark in this rapidly expanding tech scene.