Cincinnati's Top 10 Startups That Tech Professionals Should Watch Out For in 2025

By Chevas Balloun

Last Updated: December 22nd 2024

Cincinnati's skyline representing a thriving startup community in Ohio 2025.

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Cincinnati's startup ecosystem is thriving in 2025, ranking #10 among Midwest startup cities. Known for excelling in healthtech and fintech, the city offers accessible resources and a lower cost of living compared to traditional tech hubs. The startup community collaborates effectively, driving innovations from AI to healthcare waste reduction. Notable startups include Level 6 Cybersecurity, Gotara, and Seam Technologies, each tackling critical industry challenges. With significant investment and a nurturing environment, Cincinnati is an ideal place for tech professionals to advance their careers.

Cincinnati's startup scene is absolutely crushing it in 2025. With 450-500 active startups and seven Fortune 500 companies, the city has become a serious player in the tech world.

According to M25's power rankings, Cincinnati holds strong at #10 among Midwest startup cities, particularly excelling in healthtech and fintech sectors.

The ecosystem is super accessible for newcomers - we've got amazing resources like Cintrifuse's Venture Velocity Program that offers more than just funding, providing mentorship and networking opportunities.

What makes Cincinnati really stand out is how the startup community works together - from early-stage companies getting their first round of funding to established players scaling up their operations.

The cost of living here is way better than traditional tech hubs, letting you stretch your salary further while working on cutting-edge projects. Whether you're into AI, healthcare tech, or fintech, Cincinnati's startup scene has something exciting to offer, making it the perfect spot to kickstart or level up your tech career.

Table of Contents

  • Methodology: How We Selected the Top 10 Startups
  • Level 6 Cybersecurity: Leading the Charge in Cyber Defense
  • Gotara: Empowering Women in STEM
  • Seam Technologies: Innovating Healthcare Waste Reduction
  • Narratize: Pioneering AI-driven Scientific Writing
  • Carefeed: Enhancing Senior Living Communication
  • Suade: Revolutionizing AI Sales Support
  • GardenIQ: Transforming E-commerce Marketing
  • Todd: Modernizing Estate Planning
  • RYN: Redefining Personal Styling with Technology
  • Cooler Keg: Innovating Portable Beverage Solutions
  • The Benefits of Focusing on Cincinnati Startups
  • Conclusion: Cincinnati’s Bright Future in Technology Innovation
  • Frequently Asked Questions

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Methodology: How We Selected the Top 10 Startups

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In picking Cincinnati's hottest startups for 2025, we kept it real with solid data and insider knowledge. Main Street Ventures helped shape our criteria by showing what makes startups funding-worthy - from retail innovations to tech breakthroughs.

We looked at three main things: funding success, cool tech solutions, and actual results. The money part was crucial - we checked which startups were getting serious financial backing.

What's super interesting is how the Founder Institute's program has been helping these startups turn their ideas into fundable businesses since 2009, giving them a major edge in our selection process.

The innovation factor? That's where we got excited about companies doing things differently. Take some of the Inno Under 25 winners - they're crushing it with fresh ideas in AI, sports tech, and social impact ventures.

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Level 6 Cybersecurity: Leading the Charge in Cyber Defense

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Level 6 Cybersecurity has established itself as a game-changing force in Cincinnati's tech scene, bringing fresh innovations to digital defense. Their flagship product, LISN (Level 6 Infosec Strategy Network), leverages AI-powered analytics to help cybersecurity decision-makers tackle complex security challenges with data-driven intelligence.

Recent statistics show why their work matters - 84% of companies reported direct impacts from cyber attacks in 2024, with identity-based attacks accounting for 80% of all security incidents.

Level 6's approach to addressing these threats has earned recognition, as shown by their 2023 Top InfoSec Innovator Award.

As a minority-owned family business with 18 team members, they're proving that innovative solutions can come from focused, specialized teams. Their patent-pending platform analyzes global cyber-strategy data to calculate the effectiveness of various security approaches, helping organizations optimize their cybersecurity investments through real-world data and artificial intelligence.

The platform specifically targets key challenges like identity sprawl, which has doubled for 81% of organizations in the past decade, and the rising threat of adversarial AI attacks.

Looking ahead to 2025, Level 6 continues to expand its services, focusing on delivering measurable ROI for cybersecurity strategies based on industry-specific data.

Their success in joining the Retail & Hospitality ISAC demonstrates their growing influence in specialized sectors, making them a standout choice for tech professionals interested in the intersection of AI and cybersecurity.

Gotara: Empowering Women in STEM

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Gotara is changing the game for women in STEM+ with their innovative global career growth platform. Founded by D. Sangeeta, a former Amazon executive, the platform tackles a crucial issue: 40% of women leave STEM careers within their first five years.

Through their signature STAR Nano-Learning program, Gotara has achieved incredible results - participants show a 94% skill improvement rate. What makes them stand out is their unique approach to mentorship and career development, offering 24/7 anonymous support that lets women discuss workplace challenges freely.

Their impact is real - they've expanded to serve members in 163 countries, and their corporate partnerships with giants like Cisco and BrandSafway are showing amazing results.

For instance, BrandSafway reported 100% of participants successfully applying their new skills at work.

Looking ahead to 2025, Gotara is positioned to make an even bigger impact on closing the gender gap in STEM fields. Their approach isn't just about individual success - it's about transforming entire organizations.

By addressing workplace culture issues and providing practical solutions for career advancement, they're creating lasting change in the tech industry. With women leaving the workforce at twice the rate of men, Gotara's platform isn't just nice to have - it's essential for the future of tech.

Fill this form to download every syllabus from Nucamp.

And learn about Nucamp's Coding Bootcamps and why aspiring developers choose us.

Seam Technologies: Innovating Healthcare Waste Reduction

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Seam Technologies is transforming healthcare waste management in Cincinnati's startup landscape. Their impact is crucial, as research shows that waste treatment significantly contributes to the healthcare sector's carbon footprint.

The company tackles the massive challenge of managing the 6,600 tons of daily healthcare waste in the United States, offering smart solutions that merge technology with sustainability.

Their systems help prevent the release of chemical and biological hazards into the environment, while their data-driven approach enables healthcare facilities to track and optimize their waste management processes.

The recent $4 million seed funding boost proves investors are backing Seam's vision.

Their compaction technology has been shown to seriously reduce waste volume and lower disposal fees.

Their pilot programs at major hospitals have cut waste output by 30%, saving money and helping the environment. The company combines high-tech sorting systems with smart analytics to tackle this complex problem head-on.

  • Advanced AI-powered waste sorting: The company employs AI-powered waste sorting technology.
  • Real-time tracking and analytics: Their system offers real-time tracking and analytics.
  • Custom solutions for different facility sizes: They provide custom solutions tailored to differing facility sizes.
  • Proven waste reduction results: Seam Technologies boasts proven results in waste reduction.

As someone starting in tech, I'm genuinely excited about what Seam Technologies is doing.

They're not just another startup - they're actually making a difference in healthcare while creating real tech jobs in Cincinnati. If you're looking to work somewhere that combines cutting-edge technology with environmental impact, Seam Technologies should definitely be on your radar.

Narratize: Pioneering AI-driven Scientific Writing

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Narratize is changing the game in Cincinnati's startup scene with their AI-powered approach to scientific and technical writing. Their purpose-built platform for innovators transforms complex research and technical information into clear, engaging content that actually makes sense.

What's really cool is their Article Analyzer tool, which helps teams cut through dense technical reports in minutes instead of hours, saving R&D professionals nearly 12 hours every week.

The platform is seriously smart - it handles everything from research papers to technical documentation, and it's getting attention from major players in science and tech industries.

The platform's specialized features include proprietary narrative algorithms and expert-extracted insights, which is pretty next-level compared to basic AI writing tools.

What makes Narratize stand out is how it combines AI power with real scientific expertise - they've got PhD-level communicators behind the scenes making sure everything stays accurate and legit.

Their focus on technical accuracy while keeping things readable is exactly what researchers and tech companies need right now. They're becoming such a big deal in Cincinnati's tech scene - they're solving a real problem that tons of companies face when trying to communicate complex ideas.

The platform can handle all sorts of content, from white papers to clinical reports, and it's helping companies get their innovations to market way faster than before.

For anyone interested in where AI and scientific communication are headed, Narratize is definitely one to watch.

Fill this form to download every syllabus from Nucamp.

And learn about Nucamp's Coding Bootcamps and why aspiring developers choose us.

Carefeed: Enhancing Senior Living Communication

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Carefeed is transforming senior living communication through its cloud-based platform that brings residents, families, and care providers closer together.

As a recent $3 million funding round shows, investors are betting big on their vision to modernize senior care communications.

The platform stands out with its resident-focused approach, offering everything from digital admission processes to secure messaging and online payments - all without requiring seniors to download complicated apps.

The all-in-one platform eliminates the need for multiple logins and systems, making life easier for both staff and residents.

Their technology has shown impressive results, with some communities reporting a 50% increase in family participation at events thanks to their RSVP feature.

The platform seamlessly integrates with existing healthcare systems, automating previously paper-based processes like admission agreements and care conference scheduling.

Looking ahead to 2025, Carefeed is positioned to be a major player in the senior care tech space, especially as more facilities realize the need to upgrade their communication systems.

Their focus on user-friendly design specifically for seniors, combined with robust features like automated surveys and secure payment processing, makes them a standout in the industry.

Plus, their commitment to HIPAA compliance and data security shows they're serious about protecting sensitive healthcare information. For tech professionals looking to make a real difference in healthcare, Carefeed represents exactly where the industry is heading - smart, integrated solutions that actually improve people's lives.

Suade: Revolutionizing AI Sales Support

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Suade has transformed from its 2014 beginnings as a RegTech innovator into a powerhouse platform that's reshaping how businesses handle their regulatory and sales operations.

Certified with ISO-27001 and SOC 2, Suade's platform combines smart automation with real-time analysis to deliver game-changing results.

Their latest feature set includes adaptive scripts and instant feedback tools that help sales teams crush their targets. The platform's pre-call information and post-call analysis are seriously next-level, giving teams the data they need to improve with every interaction.

What's really cool about Suade is how they've secured major backing - their Series A funding brought in some heavy hitters, including former CEOs from Citigroup and Thomson Reuters.

Their CEO, Mary Gonzalez, has been clear about their mission to revolutionize how companies handle regulatory requirements through machine learning and natural language processing.

The platform now helps financial institutions automate their reporting while making sure they stay compliant with regulations.

What sets Suade apart is their commitment to constant innovation.

Their AI email scheduler automates the entire scheduling process, handling follow-ups and rescheduling without any manual work needed. The platform's also got some serious analytics capabilities that help teams track performance and spot areas for improvement.

Looking ahead to 2025, Suade is positioned to be a major player in both regulatory tech and sales enablement, making it a must-watch for anyone interested in where tech is headed.

GardenIQ: Transforming E-commerce Marketing

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In 2025, GardenIQ is revolutionizing e-commerce marketing through innovative tech solutions and smart partnerships. Their recent collaboration with Bidmath showcases their commitment to AI-powered programmatic advertising and data-driven strategies.

The platform's growth has been remarkable, with their market value reaching $58.9 billion in 2023 and projected to grow at a 6.2% CAGR through 2030.

They're seriously crushing it with their tech stack that includes machine learning for personalized customer journeys, dynamic pricing, and next-level SEO optimization.

What's really cool is how they're using AI-driven predictive analytics to decode consumer trends and optimize supply chain management - something that's totally changing the game for their clients.

Their platform consistently delivers a 30% boost in online sales within six months, which is pretty impressive. The numbers don't lie - they're targeting $15 million in revenue by the end of 2025, and honestly, looking at their growth trajectory, they might even surpass that.

GardenIQ isn't just another tech company; they're setting new standards for how businesses handle digital marketing and customer engagement. Their focus on scalable solutions and data-driven strategies makes them a must-watch player in the Cincinnati tech scene.

Todd: Modernizing Estate Planning

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BeyondWill (formerly Todd) is revolutionizing estate planning with their fresh take on digital solutions. Based in Cincinnati's Over-the-Rhine district, this startup just secured $1.2 million in pre-seed funding from local investors, proving there's serious backing for their mission to modernize estate planning.

The platform tackles a massive problem - there's over $1 billion in unclaimed life insurance and $1.4 trillion in forgotten 401(k)s just sitting there. What sets them apart is their smart approach to making estate planning actually accessible, using AI to guide users through every step.

With four full-time employees and plans to double their team by mid-2025, they're growing fast but staying focused on their core mission. They're not just another tech startup - they're working with employers to include estate planning in benefits packages, which is honestly brilliant considering how only 25% of American households have estate planning documents in place.

Their platform keeps everything updated automatically, making sure your important documents don't get lost in the shuffle of life. The team's strategy of targeting both individual consumers and professional advisers shows they understand the market needs from multiple angles.

What's really cool is how they're using technology to solve real problems while keeping their roots firmly planted in Cincinnati's growing tech scene.

RYN: Redefining Personal Styling with Technology

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RYN is changing the game in personal styling with its virtual closet and styling app, created by UC graduate Camryn Ellis.

The app scans your camera roll to detect clothes and keeps track of your recent purchases, making it super easy to organize your wardrobe. What makes it stand out from other personal styling apps is its custom outfit recommendations based on what you already own, plus a cool virtual try-on feature that works like Instagram and Snapchat filters.

The app tackles the real struggle of finding the perfect outfit without having to go on a shopping spree - everything you need might already be in your closet!

Ellis, who studied international business and entrepreneurship at UC's Lindner College of Business, has already scored some major wins with RYN (previously known as Sty/e).

The startup landed in the top three at the Morning Mentoring program and won multiple pitch competitions, including UC's Elevator Pitch competition.

With $5,500 in grant funding and support from UC's Venture Lab, RYN has built a strong foundation, connecting with experts in fashion, software development, and machine learning.

RYN is accepting beta testers right now, with plans to launch publicly in early 2024.

The app aims to solve common styling challenges by making fashion more accessible and helping users make the most of their existing wardrobes. For anyone who's ever stood in front of their closet feeling stuck, RYN might just be the solution we've been waiting for.

It's seriously cool to see a Cincinnati startup taking on the fashion tech world with such an innovative approach.

Cooler Keg: Innovating Portable Beverage Solutions

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Covington-based Cooler Keg is revolutionizing the way we enjoy drinks on the go with their stainless steel portable draft system.

This innovative startup made waves at CES 2024, where they unveiled their collaboration with Ottonomy to create the Ottobot Brew, an autonomous beverage-serving robot perfect for stadiums, hotels, and public events.

The system's impressive specs include two 228-ounce refillable kegs that can hold up to 36 beers or 72 cocktails, making it seriously versatile for any outdoor gathering.

What makes this startup stand out is their successful crowdfunding campaign and rapid market entry.

After securing strong pre-orders through Indiegogo, they've already started shipping units to eager customers. The system, priced at $949.99 with free shipping, features a food-grade CO₂ driven draft system with double taps, custom-fit ice packs, and the flexibility to convert back to a regular cooler.

Thanks to support from the UC Venture Lab, they're scaling quickly, with 1,200 coolers arriving in batches through March 2024.

The future looks bright for Cooler Keg, especially with their strategic partnerships and expanding market presence.

Their system works with various beverages including beer, cocktails, hard seltzers, and even mocktails, targeting diverse customers from breweries to corporate clients.

The partnership with Ottonomy signals their commitment to innovation, potentially transforming beverage service at large venues and corporate campuses. This combination of portability, versatility, and cutting-edge tech positions Cooler Keg as a serious contender in the beverage industry.

The Benefits of Focusing on Cincinnati Startups

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Cincinnati's startup scene is absolutely crushing it right now! Tech startups are generating over $4 billion annually and supporting more than 50,000 jobs, making this city a seriously hot spot for tech innovation.

The city's cost of living is nearly 10% below the national average, which means more money in your pocket while you build your career. Cool startups like Cooler Keg, RYN, and Preservation Bio are making waves with groundbreaking tech solutions.

What makes this even better is the University of Cincinnati's role in the startup community - they're actually outperforming Yale, Harvard, and MIT in producing founders who launch billion-dollar startups.

The support system here is incredible, with organizations like Cintrifuse investing over $50 million in early-stage startups since 2012. The city's unique blend of seasoned workforce talent from Fortune 500 companies means you're working alongside people who really know their stuff.

Plus, with places like The Union Hall and Hillman Accelerator providing awesome co-working spaces, you're never far from your next big opportunity. The startup community here is tight-knit but welcoming, and between Cincinnati Startup Week and various tech meetups, there's always a chance to network and learn.

If you're looking to jump into tech, Cincinnati's startup scene is where it's at - it's growing fast, the opportunities are real, and the community is ready to help you succeed.

Conclusion: Cincinnati’s Bright Future in Technology Innovation

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Cincinnati is making waves in the tech world as we head into 2025! Recent development plans show massive investments in infrastructure and innovation hubs across the city.

What's really exciting is how the city's tech scene is evolving - we're not just talking about startups anymore, but established companies making big moves too.

The latest data from tech leaders shows that organizations are actively building data-driven cultures and pushing the boundaries of AI implementation.

What's super cool is how Cincinnati's data and analytics leaders are collaborating to shape the future of tech in our city.

Major players like 84.51 and First Financial Bank are leading the charge in AI innovation, while smaller startups are bringing fresh ideas to the table. The city's projected economic impact from tech growth is looking absolutely incredible, with estimates suggesting over $150 million in new opportunities.

If you're in tech or thinking about jumping in, Cincinnati is the place to be right now.

The emerging tech community is super welcoming and there are tons of opportunities to get involved.

Whether you're into AI, data science, or cybersecurity, companies here are hiring like crazy and offering competitive salaries. Plus, with all these new development projects and tech hubs popping up, the networking possibilities are endless.

The future of Cincinnati's tech scene isn't just bright - it's blazing!

Frequently Asked Questions

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What makes Cincinnati a notable tech hub in 2025?

In 2025, Cincinnati is ranked #10 among Midwest startup cities, especially excelling in healthtech and fintech sectors. The city's startup ecosystem offers ample resources for newcomers, with affordable living costs compared to traditional tech hubs. Additionally, Cincinnati's vibrant startup community is known for its collaborative nature, providing a unique space for tech professionals to grow their careers.

How were the top 10 startups in Cincinnati for 2025 selected?

The selection of Cincinnati's top startups was based on three main criteria: funding success, innovation in tech solutions, and real-world results. The process was informed by solid data and insider knowledge, focusing on startups that demonstrate potential for strong financial backing and pioneering tech innovations. Support from initiatives that help convert ideas into viable businesses played a significant role in the selection process.

What innovative solutions does Level 6 Cybersecurity offer?

Level 6 Cybersecurity is recognized for its AI-powered platform that enhances digital defense strategies. The company addresses key cybersecurity challenges like identity sprawl and adversarial AI attacks with their patent-pending technology. Their focus on providing measurable ROI and industry-specific data-driven strategies has earned them a growing influence in specialized sectors like retail and hospitality cybersecurity.

How is Gotara impacting the STEM community?

Gotara is transforming the landscape for women in STEM by offering a global career growth platform that's available in 163 countries. Their STAR Nano-Learning program shows a 94% skill improvement rate. Gotara provides 24/7 anonymous support for discussing workplace challenges and collaborates with large corporations to enhance organizational culture and address gender gaps in tech fields.

What unique market solutions is Seam Technologies providing?

Seam Technologies is revolutionizing healthcare waste management by integrating advanced AI-powered waste sorting, real-time tracking, and custom solutions for various facility sizes. Their data-driven approach has successfully reduced waste by 30% in pilot programs, demonstrating significant cost savings and environmental benefits, which aligns with their sustainable vision backed by substantial investor support.

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Chevas Balloun

Director of Marketing & Brand

Chevas has spent over 15 years inventing brands, designing interfaces, and driving engagement for companies like Microsoft. He is a practiced writer, a productivity app inventor, board game designer, and has a builder-mentality drives entrepreneurship.